Elevated Cardiac Output (co) without Elevated O2 Delivery (qo2) Does Not Protect against Metabolic Acidosis during Sepsis in Piglets

Abstract

Infants infected with Group B Streptococcus (GBS) develop reduced CO, reduced QO2, and metabolic acidosis. We investigated whether reduced CO is a necessary prerequisite for acidosis during GBS sepsis. Piglets (n=16) were anaesthetized and ventilated. Blood pressure, left atrial pressure (LAP), and CO were measured. Blood gases and O2 contents were… (More)
DOI: 10.1203/00006450-198704010-00240

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