Elevated CC chemokine level in bronchoalveolar lavage fluid is predictive of a poor outcome of idiopathic pulmonary fibrosis.

@article{Shinoda2009ElevatedCC,
  title={Elevated CC chemokine level in bronchoalveolar lavage fluid is predictive of a poor outcome of idiopathic pulmonary fibrosis.},
  author={Hiromi Shinoda and Sadatomo Tasaka and Seitaro Fujishima and Wakako Yamasawa and Keisuke Miyamoto and Yasushi Nakano and Hirofumi Kamata and Naoki Hasegawa and Akitoshi Ishizaka},
  journal={Respiration; international review of thoracic diseases},
  year={2009},
  volume={78 3},
  pages={285-92}
}
BACKGROUND CC chemokines play important roles in the pathogenesis of interstitial lung diseases. Elevated CC chemokine levels have been observed in bronchoalveolar lavage (BAL) fluid of patients with idiopathic pulmonary fibrosis (IPF). OBJECTIVES We aimed to examine whether the levels of four CC chemokines, i.e. monocyte chemoattractant protein-1 (MCP-1/CCL2), macrophage inflammatory protein-1 alpha (MIP-1 alpha/CCL3), thymus- and activation-regulated chemokine (TARC/CCL17), and macrophage… CONTINUE READING