Elevated C-reactive protein in the diagnosis, prognosis, and cause of cancer

  title={Elevated C-reactive protein in the diagnosis, prognosis, and cause of cancer},
  author={Kristine H{\o}jgaard Allin and B{\o}rge Gr{\o}nne Nordestgaard},
  journal={Critical Reviews in Clinical Laboratory Sciences},
  pages={155 - 170}
The aim of this review is to summarize present evidence of an association between circulating levels of C-reactive protein (CRP) and cancer risk, and to evaluate whether elevated circulating CRP levels cause cancer. Additionally, the review provides background information on the acute-phase response, chronic inflammation, the molecular biology, function and measurement of CRP, circulating levels of CRP in health and disease, the principle of Mendelian randomization, the association between… 
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The present torrent of studies in a large number of diseases and associated conditions has highly elucidated the role of CRP as a therapeutic and research reagent and the future prospect of this review lies in the applicability of CRp as a molecule in understanding and monitoring of the biology of disease.
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Plasma C-Reactive Protein and Risk of Cancer: A Prospective Study from Greece
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C-reactive protein levels, variation in the C-reactive protein gene, and cancer risk: the Rotterdam Study.
  • C. Siemes, L. Visser, B. Stricker
  • Medicine
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • 2006
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