Elevated Akt activation and its impact on clinicopathological features of renal cell carcinoma.

@article{Horiguchi2003ElevatedAA,
  title={Elevated Akt activation and its impact on clinicopathological features of renal cell carcinoma.},
  author={Akio Horiguchi and Mototsugu Oya and Atsushi Uchida and Ken Marumo and Masaru Murai},
  journal={The Journal of urology},
  year={2003},
  volume={169 2},
  pages={
          710-3
        }
}
  • Akio Horiguchi, Mototsugu Oya, +2 authors Masaru Murai
  • Published in The Journal of urology 2003
  • Medicine
  • PURPOSE Akt has been implicated in the pathogenesis and progression of numerous human malignant tumors because Akt regulates many key effector molecules involved in controlling the balance of survival and apoptosis. Elevated Akt activation has been demonstrated in various types of malignant tumors. In the current study we evaluated Akt activation in renal cell carcinoma and investigated its association with pathological features and clinical outcome. MATERIALS AND METHODS Akt activation was… CONTINUE READING

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