Elements of neural adhesion molecules and a yeast vacuolar protein sorting receptor are present in a novel mammalian low density lipoprotein receptor family member.

@article{Yamazaki1996ElementsON,
  title={Elements of neural adhesion molecules and a yeast vacuolar protein sorting receptor are present in a novel mammalian low density lipoprotein receptor family member.},
  author={Hitoshi Yamazaki and Hideaki Bujo and Jun Kusunoki and Kohji Seimiya and Tatsuro Kanaki and Nobuhiro Morisaki and Wolfgang Johann Schneider and Yasushi Saito},
  journal={The Journal of biological chemistry},
  year={1996},
  volume={271 40},
  pages={24761-8}
}
Normal cell development depends to a large part on multifunctional proteins that have evolved by recombination of proven modular elements. We now have discovered and characterized in rabbit such a multi-domain protein, and classify it as novel member of the low density lipoprotein (LDL) receptor gene family. The extracellular portion of the approximately 250-kDa membrane protein, termed LR11, contains a cluster of 11 LDL receptor ligand binding repeats, a group of 5 LDL receptor "YWTD" repeats… CONTINUE READING

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