Elements of cancer immunity and the cancer–immune set point

@article{Chen2017ElementsOC,
  title={Elements of cancer immunity and the cancer–immune set point},
  author={Daniel S Chen and Ira Mellman},
  journal={Nature},
  year={2017},
  volume={541},
  pages={321-330}
}
Immunotherapy is proving to be an effective therapeutic approach in a variety of cancers. But despite the clinical success of antibodies against the immune regulators CTLA4 and PD-L1/PD-1, only a subset of people exhibit durable responses, suggesting that a broader view of cancer immunity is required. Immunity is influenced by a complex set of tumour, host and environmental factors that govern the strength and timing of the anticancer response. Clinical studies are beginning to define these… 

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