Elements essential for processing intronic U14 snoRNA are located at the termini of the mature snoRNA sequence and include conserved nucleotide boxes C and D.

@article{Watkins1996ElementsEF,
  title={Elements essential for processing intronic U14 snoRNA are located at the termini of the mature snoRNA sequence and include conserved nucleotide boxes C and D.},
  author={Nicholas James Watkins and R. D. Leverette and Ling Xia and Matthew T Andrews and E. S. Maxwell},
  journal={RNA},
  year={1996},
  volume={2 2},
  pages={118-33}
}
Essential elements for intronic U14 processing have been analyzed by microinjecting various mutant hsc70/Ul4 pre-mRNA precursors into Xenopus oocyte nuclei. Initial truncation experiments revealed that elements sufficient for U14 processing are located within the mature snoRNA sequence itself. Subsequent deletions within the U14 coding region demonstrated that only the terminal regions of the folded U14 molecule containing con- served nucleotide boxes C and D are required for processing… CONTINUE READING
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