Elements and the TEF-1 Family of Transcription Factors in Muscle Development

Abstract

MCAT elements are located in the promoter-enhancer regions of cardiac, smooth, and skeletal muscle-specific genes including cardiac troponin T, -myosin heavy chain, smooth muscle -actin, and skeletal -actin, and play a key role in the regulation of these genes during muscle development and disease. The binding factors of MCAT elements are members of the… (More)

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