Elemental signals regulating eosinophil accumulation in the lung.

@article{Foster2001ElementalSR,
  title={Elemental signals regulating eosinophil accumulation in the lung.},
  author={Paul S Foster and Arne W Mould and Ming Yang and Joanne Mackenzie and Joerg Mattes and Simon P Hogan and Surendran Mahalingam and Andrew N. J. McKenzie and Marc E Rothenberg and Ian G. Young and Klaus Ingo Matthaei and Dianne C. Webb},
  journal={Immunological reviews},
  year={2001},
  volume={179},
  pages={173-81}
}
In this review we identify the elemental signals that regulate eosinophil accumulation in the allergic lung. We show that there are two interwoven mechanisms for the accumulation of eosinophils in pulmonary tissues and that these mechanisms are linked to the development of airways hyperreactivity (AHR). Interleukin-(IL)-5 plays a critical role in the expansion of eosinophil pools in both the bone marrow and blood in response to allergen provocation of the airways. Secondly, IL-4 and IL-13… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 81 extracted citations

GS143, an IkappaB ubiquitination inhibitor, inhibits allergic airway inflammation in mice.

Biochemical and biophysical research communications • 2008
View 3 Excerpts
Highly Influenced

[Role of eotaxin in the pathophysiology of asthma].

Pneumonologia i alergologia polska • 2007
View 4 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…