Electrothrombosis of saccular aneurysms via endovascular approach. Part 1: Electrochemical basis, technique, and experimental results.

@article{Guglielmi1991ElectrothrombosisOS,
  title={Electrothrombosis of saccular aneurysms via endovascular approach. Part 1: Electrochemical basis, technique, and experimental results.},
  author={G. Guglielmi and F. Vi{\~n}uela and I. Sepetka and V. Macellari},
  journal={Journal of neurosurgery},
  year={1991},
  volume={75 1},
  pages={
          1-7
        }
}
Eleven experimental saccular aneurysms were created on the common carotid artery of swine. Between 3 and 15 days after creation of these aneurysms, they were thrombosed via an endovascular approach, using a very soft detachable platinum coil delivered through a microcatheter positioned within the aneurysm. This detachable platinum coil was soldered to a stainless steel delivery guidewire. Intra-aneurysmal thrombosis was then initiated by applying a low positive direct electric current to the… Expand
Endovascular electrocoagulation: concept, technique, and experimental results.
TLDR
Endovascular electrocoagulation is a rapid method of achieving vessel occlusions and may be a useful and controllable embolotherapeutic technique when expeditious occlusion of small vessels and distal superselectivity are desired. Expand
The GDC System in the Treatment of Intracranial Aneurysms
TLDR
1"4•7•5S, an endovascular method with electrolytically detachable platinum coils (Guglielmi Detachable; Coil-Target Therapeutics, Freemont, California) has been developed to provide a less invasive and safer method of treatment for intracranial aneurysms. Expand
Guglielmi detachable coil embolization of intracranial aneurysms.
Today, the Guglielmi Detachable Coil (GDC) technique is the primary endovascular modality used for the endovascular occlusion of intracranial aneurysms carrying a high surgical risk of morbidity andExpand
Endovascular treatment of cerebral aneurysms: An in vitro study with detachable platinum coils and tricellulose acetate polymer.
TLDR
Knowledge of the volumetric ratio of maximal dense packing was useful for effective filling with coils and tricellulose acetate polymer in relation to the aneurysm volume. Expand
The nature of thrombosis induced by platinum and tungsten coils in saccular aneurysms.
TLDR
The coil type influenced the initial cellular response but had little effect on the rate or degree to which blood clot within the aneurysm was replaced by fibrous tissue. Expand
Placement of mechanically detachable spiral coils in the endovascular treatment of intracranial aneurysms. Work in progress.
TLDR
The pliable, soft, retrievable MDS system provides instantaneous release of a spiral coil in the endovascular, endosaccular occlusion of intracranial aneurysms. Expand
Direct thrombosis of experimental aneurysms with cellulose acetate polymer (CAP): technical aspects, angiographic follow up, and histological study.
TLDR
Using an endovascular approach, direct thrombosis of cerebral aneurysms with CAP is safe and effective, and this technique may prove to be an alternative treatment for such aneurYSms, however, there is a potential risk of regrowth or rupture of aneuryms that retain a residual neck and long-term follow-up studies will be required. Expand
Microsurgically produced bifurcation aneurysms in a rabbit model for endovascular coil embolization.
TLDR
The authors present a detailed account of the microsurgical production of bifurcation aneurysms in chinchilla rabbits for basic studies of endovascular coil embolization of aneurYSms, and a general overestimation of the radiological degree ofAneurysm obliteration was found. Expand
Endovascular treatment of posterior circulation aneurysms by electrothrombosis using electrically detachable coils.
TLDR
It is suggested that this technique is a viable alternative in the management of patients with posterior fossa aneurysms associated with high surgical risk and longer angiographic and clinical follow-up study is necessary to determine the long-term efficacy of this recently developed endovascular occlusion technique. Expand
Endovascular Treatment of Intracranial Aneurysms
TLDR
Continuous technical advances and increasing clinical experience with endovascular techniques as well as its minimal invasiveness have made endov vascular treatment an attractive alternative, even in patients who could be treated by conventional neurosurgical clipping. Expand
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 19 REFERENCES
Transcatheter electrocoagulation: a therapeutic angiographic technique for vessel occlusion.
TLDR
Transcatheter electrocoagulation of blood vessels using direct current applied by catheter placed electrodes has advantages over embolization since no foreign material is injected and a localized clot is produced at the tip of the guidewire but there are certain disadvantages. Expand
ELECTROTHERMIC COAGULATION OF AORTIC ANEURYSMS
Observations of inactivity in saccular aneurysms completely filled with an organized blood clot have established the efficacy of "nature's cure." The principle of inserting wire into an aneurysm toExpand
Electrothrombosis of saccular aneurysms via endovascular approach. Part 2: Preliminary clinical experience.
TLDR
It is believed that this new technology is a viable alternative in the management of patients with high-risk intracranial saccular aneurysms and may also play an important role in the occlusion of aneurYSms in the acute phase of subarachnoid hemorrhage. Expand
AN EXPERIMENTAL APPROACH TO THE PROBLEM OF CEREBRAL ANEURYSM.
TLDR
This work visualized access to the aneurysm by means of a cannula or needle introduced through a burr hole and turned to an investigation of alterations that might be produced by an electric current. Expand
ANEURYSM OF THE INTERNAL CAROTID ARTERY WITHIN THE SKULL: WIRING AND ELECTROTHERMIC COAGULATION
TLDR
The treatment of aneurysm of the internal carotid artery within the skull has received the recent attention of Dandy and Walsh and Love and this operation does not always arrest the growth of the lesion, while it does carry with it the risk of ensuing. Expand
Natural history of autologous blood clot embolization in swine.
TLDR
It is concluded that swine provide an excellent animal model for studying the natural history of arterial embolization and Amicar or heat-formed clot shows no advantage over simple autologous clot in retarding intra-arterial clot lysis, and simple autOLOGous clot is an effective material for temporary intra- arterial occlusion. Expand
Experiences with surgical thrombosis of intracranial berry aneurysms and carotid cavernous fistulas.
TLDR
It is suggested that intracavernous wire thrombosis may prove to be the treatment of choice in that it seals the fistula without impairing carotid blood flow. Expand
Electrothrombosis of carotid-cavernous fistula.
The author describes a technique for directly closing a carotid cavernous fistula with electrothrombosis while preserving the intracranial arterial circulation. Copper wires are introduced throughExpand
Treatment of thoracic aortic aneurysms by the pack method of intrasaccular wiring.
TLDR
During the nineteenth century and the early part of the twentieth, aneurysms were reputed to occur more frequently in this location than elsewhere in the body. Expand
Clinical use of transcatheter electrocoagulation.
TLDR
In vitro testing suggests that intra-arterial bipolar platinum electrodes may achieve the therapeutic objectives more rapidly and with less risk, but more investigative work is required. Expand
...
1
2
...