Electrostatics and the assembly of an RNA virus.

@article{Schoot2005ElectrostaticsAT,
  title={Electrostatics and the assembly of an RNA virus.},
  author={Paul van der Schoot and Robijn Bruinsma},
  journal={Physical review. E, Statistical, nonlinear, and soft matter physics},
  year={2005},
  volume={71 6 Pt 1},
  pages={061928}
}
Electrostatic interactions play a central role in the assembly of single-stranded RNA viruses. Under physiological conditions of salinity and acidity, virus capsid assembly requires the presence of genomic material that is oppositely charged to the core proteins. In this paper we apply basic polymer physics and statistical mechanics methods to the self-assembly of a synthetic virus encapsidating generic polyelectrolyte molecules. We find that (i) the mean concentration of the encapsidated… CONTINUE READING

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