Electrospun sulfated silk fibroin nanofibrous scaffolds for vascular tissue engineering.


One of the major downfalls of tissue-engineered small-diameter vascular grafts is the inability to obtain a confluent endothelium on the lumenal surface. Loosely attached endothelial cells (ECs) are easily separated from the vessel wall when exposed to the in vivo vascular system. Thus any denuded areas on the lumenal surface of vascular grafts may lead to… (More)
DOI: 10.1016/j.biomaterials.2011.02.002

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