Electrospun silk fibroin-based neural scaffold for bridging a long sciatic nerve gap in dogs.

@article{Xue2018ElectrospunSF,
  title={Electrospun silk fibroin-based neural scaffold for bridging a long sciatic nerve gap in dogs.},
  author={Chengbin Xue and Hui Zhu and Dehua Tan and Hechun Ren and Xiaosong Gu and Yahong Zhao and Ping Zhang and Zhichao Sun and Yumin Yang and Jianhui Gu and Yun Xin Gu},
  journal={Journal of tissue engineering and regenerative medicine},
  year={2018},
  volume={12 2},
  pages={
          e1143-e1153
        }
}
Silk fibroin (SF)-derived silkworms represent a type of highly biocompatible biomaterial for tissue engineering. We have previously investigated biocompatibility of SF with neural cells isolated from the central nervous system or peripheral nerve system in vitro, and also developed a SF-based nerve graft conduit or tissue-engineered nerve grafts by introducing bone marrow mesenchymal stem cells, as support cells, into SF-based scaffold and evaluated the outcomes of peripheral nerve repair in a… CONTINUE READING
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