Electrospun cross-linked gelatin fibers with controlled diameter: the effect of matrix stiffness on proliferative and biosynthetic activity of chondrocytes cultured in vitro.

@article{Skotak2010ElectrospunCG,
  title={Electrospun cross-linked gelatin fibers with controlled diameter: the effect of matrix stiffness on proliferative and biosynthetic activity of chondrocytes cultured in vitro.},
  author={Maciej Skotak and Sandra Noriega and Gustavo F Larsen and Anuradha Subramanian},
  journal={Journal of biomedical materials research. Part A},
  year={2010},
  volume={95 3},
  pages={828-36}
}
Nanofibrous scaffolds were prepared from gelatin solutions and were further cross-linked with glutaraldehyde (GA). The fiber diameter was varied from 100 to 1000 nm by controlling the applied voltage (4-15 kV) and the concentration of the gelatin solution (4-15%). The tensile moduli and the tensile strength of the noncross-linked scaffolds varied from 20 to 120 MPa and 0.5 to 3.5 MPa, respectively. Cross-linking with GA led to an increase in both the tensile modulus and strength and correlated… CONTINUE READING

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References

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Showing 1-10 of 39 references

Characterization of gelatin nanofibers electrospun using ethanol/formic acid/water as a solvent

  • HC Chen, WC Jao, MC. Yang
  • Polym Adv Technol
  • 2009

Helix - coil transition of gelatin : Helical morphology and stability

  • JL Gornall, EM Terentjev
  • Soft Matter
  • 2008

Helix-coil transition of gelatin: Helical morphology and stability. Soft Matter 2008;4:544–549

  • JL Gornall, EM Terentjev
  • 2008

Recent patents on electrospun biomedical nanostructures: An Overview

  • SG Kumbar, SP Nukavarapua, R James, MV Hogana, CT. Laurencin
  • Recent Pat Biomed Eng 2008;1:68–78
  • 2008

Effects of parameters on nanofiber diameter determined from electrospinning model

  • CJ Thompson, GG Chase, AL Yarin, DH Reneker
  • Polymer
  • 2007

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