Electrospun PLLA Nanofiber Scaffolds and Their Use in Combination with BMP-2 for Reconstruction of Bone Defects

@inproceedings{Schofer2011ElectrospunPN,
  title={Electrospun PLLA Nanofiber Scaffolds and Their Use in Combination with BMP-2 for Reconstruction of Bone Defects},
  author={Markus Dietmar Schofer and Philip P Roessler and Jan Schaefer and Christina Theisen and Sonja Schlimme and Johannes T. Heverhagen and Maximilian V{\"o}lker and Roland Dersch and Seema Agarwal and Susanne Fuchs-Winkelmann and J{\"u}rgen Rudolf Josef Paletta},
  booktitle={PloS one},
  year={2011}
}
INTRODUCTION Adequate migration and differentiation of mesenchymal stem cells is essential for regeneration of large bone defects. To achieve this, modern graft materials are becoming increasingly important. Among them, electrospun nanofiber scaffolds are a promising approach, because of their high physical porosity and potential to mimic the extracellular matrix (ECM). MATERIALS AND METHODS The objective of the present study was to examine the impact of electrospun PLLA nanofiber scaffolds… CONTINUE READING

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