Electrospinning of matrigel to deposit a basal lamina-like nanofiber surface.

  title={Electrospinning of matrigel to deposit a basal lamina-like nanofiber surface.},
  author={Roche C de Guzman and Jeffrey A. Loeb and Pamela VandeVord},
  journal={Journal of biomaterials science. Polymer edition},
  volume={21 8-9},
Schwann cell basal lamina is a nanometer-thin extracellular matrix layer that separates the axon-bound Schwann cells from the endoneurium of the peripheral nerve. It is implicated in the promotion of nerve regeneration after transection injury by allowing Schwann cell colonization and axonal guidance. Hence, it is desired to mimic the native basal lamina for neural tissue engineering applications. In this study, basal lamina proteins from BD Matrigel (growth factor-reduced) were extracted and… CONTINUE READING


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