Electrospinning and biocompatibility evaluation of biodegradable polyurethanes based on L-lysine diisocyanate and L-lysine chain extender.

@article{Han2011ElectrospinningAB,
  title={Electrospinning and biocompatibility evaluation of biodegradable polyurethanes based on L-lysine diisocyanate and L-lysine chain extender.},
  author={Jian Han and Run-Wu Cao and Bing Chen and Lin Ye and Ai-Ying Zhang and Jian Zhang and Zeng-Guo Feng},
  journal={Journal of biomedical materials research. Part A},
  year={2011},
  volume={96 4},
  pages={705-14}
}
A series of biodegradable polyurethanes (PUs) were synthesized using poly(ε-caprolactone) diol (PCL) to react with L-lysine ethyl ester diisocyanate (LDI) chain extend with L-lysine ethyl ester (LEE) in solution of DMF. The structure was characterized by gel permeation chromatography, ¹H-NMR, Fourier transform infrared, and DSC analyses. Mechanical property testing showed that their tensile strength rose with increasing the hard segment content with a maximum tensile strength of 34.43 ± 1.73… CONTINUE READING