Electroshock seizures protect against apoptotic hippocampal cell death induced by adrenalectomy.

@article{Masco1999ElectroshockSP,
  title={Electroshock seizures protect against apoptotic hippocampal cell death induced by adrenalectomy.},
  author={Daniel Masco and Niaz Sahibzada and Robert Switzer and Karen N Gale},
  journal={Neuroscience},
  year={1999},
  volume={91 4},
  pages={1315-9}
}
Seizures evoked by electroshock induce rapid changes in the expression of several genes in the adult brain, including those encoding for neurotrophic factors. Some of the neurotrophic factors induced by brief seizures such as basic fibroblast growth factor and nerve growth factor have been shown to have neuroprotective action. We reasoned therefore that these seizures may protect against neural injury. To test this hypothesis, we examined the effect of electroshock-induced seizures on the… CONTINUE READING
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