Electroporation of mammalian cells in a microfluidic channel with geometric variation.

@article{Wang2006ElectroporationOM,
  title={Electroporation of mammalian cells in a microfluidic channel with geometric variation.},
  author={Hsiang-Yu Wang and Chang Lu},
  journal={Analytical chemistry},
  year={2006},
  volume={78 14},
  pages={5158-64}
}
Electroporation has been widely used to load impermeant exogenous molecules into cells. Rapid electrical lysis based on electroporation has also been applied to analyze intracellular materials at single-cell level. There has been increasing demand to implement electroporation in a microfluidic format as a basic tool for applications ranging from screening of drugs and genes to studies of intracellular dynamics. In this report, we have developed a simple technique to electroporate mammalian… CONTINUE READING

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