Electroporation of asymmetric phospholipid membranes.

  title={Electroporation of asymmetric phospholipid membranes.},
  author={Andrey A Gurtovenko and Anastasia S Lyulina},
  journal={The journal of physical chemistry. B},
  volume={118 33},
As plasma membranes of animal cells are known to be asymmetric, the transmembrane lipid asymmetry, being essential for many membranes' properties and functions, should be properly accounted for in model membrane systems. In this paper, we employ atomic-scale molecular dynamics simulations to explore electroporation phenomena in asymmetric model membranes comprised of phosphatidylcholine (PC) and phosphatidylethanolamine (PE) lipid monolayers that mimic the outer and inner leaflets of plasma… CONTINUE READING
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