Electrophysiology of rabbit ventricular myocytes following sustained rapid ventricular pacing.

@article{Rozanski1997ElectrophysiologyOR,
  title={Electrophysiology of rabbit ventricular myocytes following sustained rapid ventricular pacing.},
  author={George J. Rozanski and Zhi Xu and R T Whitney and Hitochi Murakami and Irving H. Zucker},
  journal={Journal of molecular and cellular cardiology},
  year={1997},
  volume={29 2},
  pages={721-32}
}
The present study examined changes in electrophysiological properties of ventricular myocytes isolated from rabbit hearts after 2-3 weeks of rapid ventricular pacing. Left ventricular end-diastolic pressure at completion of the pacing period was nearly four-fold greater than in age-matched controls, although there was no significant change in heart weight/body weight ratio. Action potentials recorded in current-clamp mode at low stimulation frequencies were significantly longer in duration and… CONTINUE READING
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