Electrophysiology of oxytocin actions on central neurons.

  title={Electrophysiology of oxytocin actions on central neurons.},
  author={J. J. Dreifuss and Michel L Dubois-Dauphin and H{\'e}l{\`e}ne Widmer and Mario Raggenbass},
  journal={Annals of the New York Academy of Sciences},
The action of oxytocin on neurons located in the dorsal motor nucleus of the vagus nerve was studied in brain slices in vitro. It acted postsynaptically and caused a reversible, concentration-dependent excitation of vagal motoneurons in rats. This effect is specific, since it could be mimicked by a selective agonist and suppressed by an oxytocin antagonist. Single-electrode voltage-clamp recordings from rat vagal motoneurons indicated that oxytocin generates a noninactivating inward current… CONTINUE READING