Electrophysiology of dentate gyrus granule cells.

  title={Electrophysiology of dentate gyrus granule cells.},
  author={Russell A. Fricke and David A. Prince},
  journal={Journal of neurophysiology},
  volume={51 2},
The orthodromic synaptic responses, membrane properties, and responses of dentate gyrus granule cells (DGCs) to several convulsant agents were studied in the in vitro hippocampal slice preparation. Orthodromic stimulation via the perforant pathway (PP) evoked excitatory-inhibitory postsynaptic potentials (EPSP-IPSP) sequences in 27 of 34 DGCs studied. In the majority, only one action potential could be evoked by supramaximal orthodromic stimulation. In recordings from DGC somata, overshooting… CONTINUE READING