Electrophysiological effects of acute ventricular dilatation in the isolated rabbit heart.

@article{Reiter1988ElectrophysiologicalEO,
  title={Electrophysiological effects of acute ventricular dilatation in the isolated rabbit heart.},
  author={Michael Zavlanos Xiaobai Sun Jerome Reiter and David P. Synhorst and David E. Mann},
  journal={Circulation research},
  year={1988},
  volume={62 3},
  pages={554-62}
}
We examined the effects of left ventricular dilatation on epicardial pacing threshold, conduction velocity, and effective refractory period (ERP) in the isolated, retrograde perfused rabbit heart. Left ventricular size was modified by acutely changing the volume of a fluid-filled balloon anchored within the vented left ventricle. Increases in left ventricular volume, associated with increases in left ventricular end-diastolic pressure from 0 +/- 1 to 35 +/- 2 mm Hg, were not associated with… CONTINUE READING