Electrophysiological characterization of neurons in the dorsolateral pontine rapid-eye-movement sleep induction zone of the rat: Intrinsic membrane properties and responses to carbachol and orexins.

@article{Brown2006ElectrophysiologicalCO,
  title={Electrophysiological characterization of neurons in the dorsolateral pontine rapid-eye-movement sleep induction zone of the rat: Intrinsic membrane properties and responses to carbachol and orexins.},
  author={Ritchie E Brown and Stuart Winston and Radhika Basheer and Mahesh M Thakkar and R. W. McCarley},
  journal={Neuroscience},
  year={2006},
  volume={143 3},
  pages={739-55}
}
Pharmacological, lesion and single-unit recording techniques in several animal species have identified a region of the pontine reticular formation (subcoeruleus, SubC) just ventral to the locus coeruleus as critically involved in the generation of rapid-eye-movement (REM) sleep. However, the intrinsic membrane properties and responses of SubC neurons to neurotransmitters important in REM sleep control, such as acetylcholine and orexins/hypocretins, have not previously been examined in any… CONTINUE READING

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