Electrophysiological characterization of CA2 pyramidal cells from epileptic humans.

  title={Electrophysiological characterization of CA2 pyramidal cells from epileptic humans.},
  author={Anne Williamson and Dennis D. Spencer},
  volume={4 2},
The CA2 region of the hippocampus is more resistant to the principal cell loss seen in CA1 and CA3 in both animal models of temporal lobe epilepsy and in medial temporal lobe sclerosis (MTS), a common neuropathological finding in human temporal lobe epilepsy. There is extensive synaptic reorganization in the MTS hippocampi that is not seen in the hippocampi of patients with tumor-associated temporal lobe epilepsy (TTLE). The authors examined the electrophysiological properties of CA2 pyramidal… CONTINUE READING


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