Electrophysiological characterisation of the dentate gyrus in five inbred strains of mouse

@article{Bampton1999ElectrophysiologicalCO,
  title={Electrophysiological characterisation of the dentate gyrus in five inbred strains of mouse},
  author={Edward T. W. Bampton and Roy A Gray and Charles H. Large},
  journal={Brain Research},
  year={1999},
  volume={841},
  pages={123-134}
}
Transgenic or knockout mouse models provide the opportunity to study the function of disease-related or novel genes. However, a confounding factor in all such research is the genetic and phenotypic variation of the mouse strain used to construct the models. A trait which is frequently studied in transgenic models of neurological disorders is synaptic transmission and plasticity of the dentate gyrus of the hippocampus. Consequently, we have investigated the variation in this trait across five… CONTINUE READING
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