Electrophysiological basis for the bradycardic effects of 1-(1-pyrrolidinylmethyl)-2-naphthol in rodents.

Abstract

In anesthetized rats, intravenous injection of 1-(1-pyrrolidinylmethyl)-2-naphthol (TPY-beta, 0.1-1 mg/kg) induced a transient (less than 1 min) decrease in arterial blood pressure and heart rate (acute responses) followed by a delayed and sustained (greater than 10 min) bradycardic response. The electrophysiological mechanisms responsible for the… (More)

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Cite this paper

@article{Shen1992ElectrophysiologicalBF, title={Electrophysiological basis for the bradycardic effects of 1-(1-pyrrolidinylmethyl)-2-naphthol in rodents.}, author={A. Y. Shen and C L Chen and C I Lin}, journal={The Chinese journal of physiology}, year={1992}, volume={35 1}, pages={45-54} }