Electrophysiological analysis of the inhibitory effects of FMRFamide-like peptides on the pacemaker activity of gonadotropin-releasing hormone neurons.

@article{Saito2010ElectrophysiologicalAO,
  title={Electrophysiological analysis of the inhibitory effects of FMRFamide-like peptides on the pacemaker activity of gonadotropin-releasing hormone neurons.},
  author={Takeshi H. Saito and Ryo Nakane and Yasuhisa Akazome and Hideki Abe and Yoshitaka Oka},
  journal={Journal of neurophysiology},
  year={2010},
  volume={104 6},
  pages={3518-29}
}
Gonadotropin-releasing hormone (GnRH) neurons in the terminal nerve (TN) show endogenous pacemaker activity, which is suggested to be dependent on the physiological conditions of the animal. The TN-GnRH neurons have been suggested to function as a neuromodulatory neuron that regulates long-lasting changes in the animal behavior. It has been reported that the TN-GnRH neurons are immunoreactive to FMRFamide. Here, we find that the pacemaker activity of TN-GnRH neuron is inhibited by FMRFamide… CONTINUE READING
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