Electrophysiological actions of the dopamine agonist apomorphine in the paraventricular nucleus during penile erection

@article{Richards2009ElectrophysiologicalAO,
  title={Electrophysiological actions of the dopamine agonist apomorphine in the paraventricular nucleus during penile erection},
  author={Natalie Richards and Chris P Wayman and Kelly Ann Allers},
  journal={Neuroscience Letters},
  year={2009},
  volume={465},
  pages={242-247}
}
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9 Citations
Background Citations
4
Methods Citations
1

9 Citations

Citation Type

Citation Type

Neuronal activity in the hypothalamic paraventricular nucleus varies across the estrous cycle in anesthetized female rats: effects of dopamine receptor agonism.
TLDR
This study shows that PVN neuronal activity varies with hormonal state, and these neurons are differentially affected by apomorphine, suggesting two different populations of PVN neurons, and is indicative of a critical role for the PVN in female sexual function.
Comparisons of apomorphine‐induced erection and spontaneous erection in rats by telemetric assessment of intracavernosal pressure
TLDR
AIE is easy and requires less time than SE measurements, therefore, AIE could be a useful method to evaluate ICP in rats and ICP measurements using a telemetric device showed no significant difference.
Clavulanic acid induces penile erection and yawning in male rats: Comparison with apomorphine
Cligosiban, A Novel Brain-Penetrant, Selective Oxytocin Receptor Antagonist, Inhibits Ejaculatory Physiology in Rodents.
The evaluation of apomorphine for the treatment of erectile dysfunction
TLDR
Apomorphine is not a first-line treatment option for patients with ED, but may have a niche in the treatment ED in patients who have failed treatment with, or are intolerant to other well-established pharmacological treatment for ED (e.g., PDE5-Is).
The Efficacy of Using Cabergoline in Psychogenic Erectile Dysfunction Treatment (A Local Study)
TLDR
The use of combination treatment of cabercoline and tadalafil was unscathed and more operative in the treating of patients with psychogenic dysfunction erectile compared to tadalAFil monotherapy.
Hyperhomocysteinaemia in rats is associated with erectile dysfunction by impairing endothelial nitric oxide synthase activity
TLDR
Evidence is provided that HHCy is a vascular risk factor for erectile dysfunction by impairing cavernosa endothelial nitric oxide synthase activity and intake of vitamins B can alleviate this abnormality.
Central nervous system agents and erectile dysfunction.
The neurobiology of the male sexual refractory period

References

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TLDR
It is demonstrated that application of apomorphine to the paraventricular nucleus of hypothalamus elicited penile erection in the rat and indicates that PVN may be involved in the central regulation of apomorphicine-induced penile implantation in theRat.
Paraventricular nucleus lesion prevents yawning and penile erection induced by apomorphine and oxytocin but not by ACTH in rats
The septal area, site for the central regulation of penile erection during waking and rapid eye movement sleep in rats: A stimulation study
Apomorphine-induced brain modulation during sexual stimulation: a new look at central phenomena related to erectile dysfunction
TLDR
Functional magnetic resonance imaging placebo-controlled study presents the first in vivo demonstration of the apomorphine-induced modulation of cortical and subcortical brain structures in patients with psychogenic erectile dysfunction, suggesting that psychogenic impotence may be associated with previously unrecognized underlying functional abnormalities of the brain.
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Stimulation of dopamine receptors in the paraventricular nucleus of the hypothalamus of male rats induces penile erection and increases extra-cellular dopamine in the nucleus accumbens: Involvement of central oxytocin
Some proposals regarding the organization of the central nervous system control of penile erection
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TLDR
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