Electrophysiologic and electroanatomic changes in the human atrium associated with age.

@article{Kistler2004ElectrophysiologicAE,
  title={Electrophysiologic and electroanatomic changes in the human atrium associated with age.},
  author={Peter M. Kistler and Prashanthan Sanders and Simon Patrick Fynn and Irene H Stevenson and Steven J. Spence and Jitendra K. Vohra and Paul B. Sparks and Jonathan M. Kalman},
  journal={Journal of the American College of Cardiology},
  year={2004},
  volume={44 1},
  pages={109-16}
}
OBJECTIVES The purpose of this study was to characterize the pattern of atrial remodeling seen with human aging. BACKGROUND Atrial fibrillation (AF) occurs in 3% to 4% of the population over 65 years of age. It is associated with thromboembolic complications, worsening heart failure, and increased mortality, yet the electrical and structural remodeling that occurs with human aging remains unknown. METHODS Thirteen patients (66.4 +/- 1.7 years) > or =60 years (group A), 13 patients (50 +/- 2… CONTINUE READING