Electrophysiologic and behavioral effects of perinatal and acute exposure of rats to lead and polychlorinated biphenyls.

@article{Carpenter2002ElectrophysiologicAB,
  title={Electrophysiologic and behavioral effects of perinatal and acute exposure of rats to lead and polychlorinated biphenyls.},
  author={D. E. O. S. Carpenter and Rifat J. Hussain and David F Berger and John P Lombardo and Hye-Youn Park},
  journal={Environmental Health Perspectives},
  year={2002},
  volume={110},
  pages={377 - 386}
}
Lead and polychlorinated biphenyls (PCBs) both cause a reduction of intelligence quotient and behavioral abnormalities in exposed children that have features in common with attention deficit hyperactivity disorder. We have used rats as a model to study the effects of both perinatal and acute exposure to lead or PCBs in an effort to compare and understand the mechanisms of these nervous system decrements. Long-term potentiation (LTP) is an electrophysiologic measurement that correlates well with… CONTINUE READING
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Developmental exposure of rats to a reconstituted PCB mixture or Aroclor 1254 : effects on long - term potentiation and [ 3 H ] MK801 binding in occipital cortex and hippocampus

  • L Altmann, WR Numday, TR Fard, A Fastabend, H Lilienthal
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