Electrophoretic mobility-shift and super-shift assays for studies and characterization of protein-DNA complexes.

Abstract

Gene expression is in part regulated by transcription factors that bind specific sequence motifs in genomic DNA. Transcription factors cooperate with the basal machinery to upregulate or downregulate transcription. Experimental data have revealed the importance of interactions among members of distinct families of transcription factors to form complexes… (More)
DOI: 10.1007/978-1-62703-284-1_12

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