Electrophoretic and mass spectrometric strategies for profiling bacterial lipopolysaccharides.

@article{Li2005ElectrophoreticAM,
  title={Electrophoretic and mass spectrometric strategies for profiling bacterial lipopolysaccharides.},
  author={Jianjun Li and Andrew D Cox and Derek W Hood and Elke K.H. Schweda and E . Richard Moxon and James C. Richards},
  journal={Molecular bioSystems},
  year={2005},
  volume={1 1},
  pages={46-52}
}
Capillary electrophoresis (CE) is a high-resolution separation technique that has been widely used for trace analysis in biological samples. On-line capillary electrophoresis-electrospray mass spectrometry (CE-MS) was developed for the analysis of lipopolysaccharide (LPS) glycoforms from the gram-negative bacteria, Haemophilus influenzae. In this paper, we report on the application of CE-MS to characterize structural differences in O-deacylated LPS samples from H. influenzae strains Rd 11.7 and… CONTINUE READING