Electrophoretic analysis of the cleaved form of serpin, squamous cell carcinoma antigen‐1 in normal and malignant squamous epithelial tissues

@article{Nawata2003ElectrophoreticAO,
  title={Electrophoretic analysis of the cleaved form of serpin, squamous cell carcinoma antigen‐1 in normal and malignant squamous epithelial tissues},
  author={S. Nawata and Kazuyuki Nakamura and H. Hirakawa and Kotaro Sueoka and T. Emoto and A. Murakami and K. Umayahara and H. Ogata and Y. Suminami and F. Numa and H. Kato},
  journal={ELECTROPHORESIS},
  year={2003},
  volume={24}
}
The aim of this study was to detect the cleaved form of serine proteinase inhibitor (serpin), squamous cell carcinoma (SCC) antigen‐1 in normal and malignant squamous epithelial tissues, which implies the presence of its target proteinase. The cleaved SCC antigen‐1 in normal squamous epithelium was identified as a single spot with pI 6.35 and Mr 40 000 by two‐dimensional electrophoresis (2‐DE) combined with immunoblotting. Interestingly, the cleaved form showed different biochemical properties… Expand
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