Electrophilic properties of nitroheterocyclic compounds. Potential hypoxic cells radiosensitizers.

Abstract

Investigation of the reduction potential and calculation of the partition coefficient n-octanol/water allow the assessment of the potential suitability of nitropirydine N-oxide compounds in radiotherapy of cancer. Experiments were carried out using cyclic voltammetry with HMDE as working electrode. The electrode reduction of the investigated compounds is… (More)

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