Electrophilic activation of alkynes for enyne cycloisomerization reactions with in situ generated early/late heterobimetallic Pt-Ti catalysts.

@article{Talley2016ElectrophilicAO,
  title={Electrophilic activation of alkynes for enyne cycloisomerization reactions with in situ generated early/late heterobimetallic Pt-Ti catalysts.},
  author={Michael R. Talley and Ryjul W. Stokes and Whitney K. Walker and David J. Michaelis},
  journal={Dalton transactions},
  year={2016},
  volume={45 24},
  pages={
          9770-3
        }
}
In situ formation of heterobimetallic Pt-Ti catalysts enables rapid room temperature catalysis in enyne cycloisomerization reactions. The Lewis acidic titanium atom in the ligand framework is shown to be essential for fast catalysis. A range of enyne substrates are efficiently cyclized to carbocycles and heterocycles in high yield. 
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