Electrophilic Aromatic Substitution: Mechanism


Electrophilic aromatic substitution (S E Ar) is one of the most important synthetic organic reactions [1]. Since its discovery in the 1870s by Charles Friedel and James Crafts [2], it has become a general route to functionalized aromatic compounds. The chemistry is used extensively in the chemical industry, providing millions of tons of aromatic products… (More)


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