Electronmicroscopy of conjunctival biopsy in mannosidosis.


Electronmicroscopic examination was performed on conjunctival biopsies from two adolescent siblings with mannosidosis. Fibroblasts and endothelial cells contained membrane-bound vacuoles and vesicles that contained homogeneous osmiophilic globules. These vesicles seem to be pathognomonic of mannosidosis. Plasma cells also contained membrane-bound vacuoles… (More)


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@article{Yamano1981ElectronmicroscopyOC, title={Electronmicroscopy of conjunctival biopsy in mannosidosis.}, author={Toshio Yamano and Mitsuo Shimada and Shuichi Okada and Toru Yutaka and Hidetaki Yabuuchi and Akihisa Mitsudome and S Itsuki}, journal={Neurology}, year={1981}, volume={31 5}, pages={630-2} }