Electronic detection of microRNA at attomolar level with high specificity.

@article{Ramnani2013ElectronicDO,
  title={Electronic detection of microRNA at attomolar level with high specificity.},
  author={Pankaj Ghanshyam Ramnani and Yingning Gao and Metimet Ozsoz and Ashok Mulchandani},
  journal={Analytical chemistry},
  year={2013},
  volume={85 17},
  pages={
          8061-4
        }
}
Small RNA (19-23 nucleotides) molecules play an important role in gene regulation, embryonic differentiation, hematopoiesis, and a variety of cancers. Here, we present an ultrasensitive, extremely specific, label-free, and rapid electronic detection of microRNAs (miRNAs) using a carbon nanotubes field-effect transistor functionalized with the Carnation Italian ringspot virus p19 protein biosensor. miRNA-122a was chosen as the target, which was first hybridized to a probe molecule. The probe… CONTINUE READING
BETA

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 14 CITATIONS

Similar Papers

Loading similar papers…