Electronic DNA detection on semiconductor surfaces

  title={Electronic DNA detection on semiconductor surfaces},
  author={Y. Han and Eric Tan and Drew Candebat and Krisanu Bandyopadhyay and Angelika Niemz},
Electronic biosensors offer a viable alternative to optical biosensors for the rapid, specific, and sensitive detection of DNA. We are utilizing an electrolyte-oxide-semiconductor (EOS) biosensor system on a SiO2/Si surface for impedimetric detection of DNA. Detection in this system is based on the intrinsic negative charge of DNA. Hybridization of target DNA to the probe-functionalized semiconductor electrode causes a change in the surface charge density, which results in a measurable shift of… CONTINUE READING