Electronic Cigarettes

@article{Born2015ElectronicC,
  title={Electronic Cigarettes},
  author={Hayley L. Born and Michael J Persky and Dennis H. Kraus and Robert Peng and Milan R. Amin and Ryan C. Branski},
  journal={Otolaryngology–Head and Neck Surgery},
  year={2015},
  volume={153},
  pages={14 - 5}
}
Objective To introduce the otolaryngology community to the current state of research regarding electronic cigarettes, with special attention paid to mechanism, impact on health and addiction, and use in smoking cessation. Data Sources Review of Google Scholar and PubMed databases using the keywords electronic cigarettes, e-cigs, e-cigarettes, and vaping. In addition, information from media sources as well as news outlets was evaluated to gauge public perception of research findings. Review… 

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TLDR
Because a user's e-cigarette experience may significantly impact nicotine delivery, future nicotine pharmacokinetic and pharmacodynamic studies should be conducted in experienced users to accurately assess the products’ impact on public health.
Acute electronic cigarette use: nicotine delivery and subjective effects in regular users
TLDR
These findings demonstrate reliable blood nicotine delivery after the acute use of this brand/model of e-cigarette in a sample of regular users, and Tobacco-related withdrawal symptoms and urge to smoke were significantly reduced.
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If patients who smoke are unwilling to quit or cannot succeed using evidence-based approaches, e-cigarettes may be an option to be considered after discussing the limitations of current knowledge.
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In smokers not intending to quit, the use of e-cigarettes, with or without nicotine, decreased cigarette consumption and elicited enduring tobacco abstinence without causing significant side effects.
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TLDR
This systematic review appraises existing laboratory and clinical research on the potential risks from electronic cigarette use, compared with the well-established devastating effects of smoking tobacco cigarettes to indicate that electronic cigarettes are by far a less harmful alternative to smoking.
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TLDR
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There is sufficient evidence about the toxicity of nicotine and the other components that have been found in e-cigarettes, including tobacco itself, for regulatory agencies to require a list with concentrations of all e-cigarette ingredients.
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