Electron tomographic analysis of cytoskeletal cross-bridges in the paranodal region of the node of Ranvier in peripheral nerves.

@article{Perkins2008ElectronTA,
  title={Electron tomographic analysis of cytoskeletal cross-bridges in the paranodal region of the node of Ranvier in peripheral nerves.},
  author={Guy A Perkins and Gina E. Sosinsky and Sassan Ghassemzadeh and Alex Perez and Ying Z. Jones and Mark H. Ellisman},
  journal={Journal of structural biology},
  year={2008},
  volume={161 3},
  pages={469-80}
}
The node of Ranvier is a site for ionic conductances along myelinated nerves and governs the saltatory transmission of action potentials. Defects in the cross-bridging and spacing of the cytoskeleton are a prominent pathological feature in diseases of the peripheral nerve. Electron tomography was used to examine cytoskeletal-cytoskeletal, membrane-cytoskeletal, and heterologous cell connections in the paranodal region of the node of Ranvier in peripheral nerves. Focal attachment of cytoskeletal… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 19 extracted citations

Mitochondrial anchors: Positioning mitochondria and more.

Biochemical and biophysical research communications • 2018

Axonal spectrins: All-purpose fences

The Journal of cell biology • 2013
View 1 Excerpt

Systematic approaches to central nervous system myelin

Cellular and Molecular Life Sciences • 2012
View 1 Excerpt

Similar Papers

Loading similar papers…