Electron microscopic study of human immunodeficiency virus type 1 (HIV-1) core structure: two RNA strands in the core of mature and budding particles

@article{Takasaki1997ElectronMS,
  title={Electron microscopic study of human immunodeficiency virus type 1 (HIV-1) core structure: two RNA strands in the core of mature and budding particles},
  author={Tomohiko Takasaki and Ichiro Kurane and Hideki Aihara and Noriaki Ohkawa and Julie Yamaguchi},
  journal={Archives of Virology},
  year={1997},
  volume={142},
  pages={375-382}
}
The basic structure of human immunodeficiency virus type 1 (HIV-1) has been investigated morphologically; however, the internal structure of HIV-1 core is not well understood. We studied the internal structures by transmission electron microscopy. We modified the method for electron staining of ultrathin sections and processed electron microscopic photographs using a computer. We confirmed that a mature HIV-1 particle had two copies of RNA strands in a cone-shaped core. These two RNA strands… CONTINUE READING

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