Electron microscopic observations of leukoplakia


Malignant dyskeratosis in leukoplakia was studied by electron microscopy. Fine structures of malignant dyskeratosis could be characterized by the aggregation of tonofilaments and the loss of desmosomes. The aggregated tonofilaments were found in suprabasal spinous cells and seemed to increase in size and number as the spinous cell moved up. The final stage… (More)
DOI: 10.1007/BF00596240


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