Electron density imaging of protein films on gold-particle surfaces with transmission electron microscopy.

@article{Jrgens1999ElectronDI,
  title={Electron density imaging of protein films on gold-particle surfaces with transmission electron microscopy.},
  author={L J{\"u}rgens and Alfons Nichtl and Ulf Werner},
  journal={Cytometry},
  year={1999},
  volume={37 2},
  pages={
          87-92
        }
}
BACKGROUND Surface bound proteins on colloid particles are widely used in biotechnological applications such as diagnostics or separation. Analysis of colloid surfaces by imaging methods provides information on the structure of these protein films, and an understanding of the functional relationships of biomolecules immobilised on solid surfaces. METHODS In order to visualise protein molecules organised in films on surfaces of nano-sized gold-particles, an electron-microscopic approach based… CONTINUE READING