Electron capture dissociation of substance P using a commercially available Fourier transform ion cyclotron resonance mass spectrometer.

@article{Axelsson1999ElectronCD,
  title={Electron capture dissociation of substance P using a commercially available Fourier transform ion cyclotron resonance mass spectrometer.},
  author={Jan Peter Axelsson and Magnus Palmblad and Kristina H{\aa}kansson and Per H{\aa}kansson},
  journal={Rapid communications in mass spectrometry : RCM},
  year={1999},
  volume={13 6},
  pages={474-7}
}
Electron capture dissociation of the peptide Substance P is reported for the first time, with an unmodified, commercially available Fourier transform ion cyclotron resonance (FTICR) mass spectrometer. The fragmentation pattern is compared with that obtained with collisionally induced dissociation of the ions in the electrospray ion source, and note that electron capture dissociation gives a more easily interpreted spectrum, showing mainly C-fragments. With the exception of the proline residues… CONTINUE READING

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