Electron Tomography of Vesicles

  title={Electron Tomography of Vesicles},
  author={C. Charles Michel},
  • C. Michel
  • Published 2012
  • Chemistry, Medicine
  • Microcirculation
Please cite this paper as: Michel CC. Electron tomography of vesicles. Microcirculation 19: 473–476, 2012. 
2 Citations
Pericytes on placental capillaries in terminal villi preferentially cover endothelial junctions in regions furthest away from the trophoblast
Data suggest that the localisation of pericytes on the villous capillary is not random but organised in relation to both endothelial junctions and the location of adjacent trophoblast, which suggests that pericyte coverage may favour capillary permeability in regions that are most important for exchange, but limit capillary porousness in other regions. Expand
Functional Ultrastructure


Three‐Dimensional Analysis and Computer Modeling of the Capillary Endothelial Vesicular System with Electron Tomography
Three‐dimensional analysis and computer modeling of the capillary endothelial vesicular system with electron tomography with electrontomography is presented. Expand
3D Reconstruction of the Glycocalyx Structure in Mammalian Capillaries using Electron Tomography
Three-dimensional reconstruction of the glycocalyx structure in mammalian capillaries using electron tomography shows clear relationships between EMT activity and apoptosis in response to EMT-guided cell reprograming. Expand
Electron tomography at 2.4 Å resolution
Extended abstract of a paper presented at Microscopy and Microanalysis 2012 in Phoenix, Arizona, USA, July 29 – August 2, 2012.
Pathways of Macromolecular Extravasation Across Microvascular Endothelium in Response to VPF/VEGF and Other Vasoactive Mediators
Objective: The goal of these studies was to define the anatomic pathways by which circulating macromolecules extravasate from the hyperpermeable microvessels that supply tumors and from normalExpand
Vesicular transport in capillary endothelium: does it occur?
A reinterpretation of previous studies of vesicular transport shows that they are equally compatible with the present view that plasmalemmal vesicles are static elements of invaginations of the endothelial surface membrane. Expand
Endothelial plasmalemmal vesicles as elements in a system of branching invaginations from the cell surface.
It is proposed that cytoplasmic vesicles in endothelial cells are elements of branching, permanent or semipermanent invaginations of the plasmalemma. Expand
Reconstruction of Three Dimensional Structures from Electron Micrographs
General principles are formulated for the objective reconstruction of a three dimensional object from a set of electron microscope images. These principles are applied to the calculation of a threeExpand
The role of vesicles in the transport of ferritin through frog endothelium.
It is suggested that the early constant labelling of cytoplasmic and abluminal vesicles is consistent with the existence of vesicular channels, and albumin may affect vesicle transport by its interaction with the endothelial glycocalyx. Expand
Transcapillary transport of solute by the endothelial vesicular system: evidence from thin serial section analysis.
Observations strongly implicate transcellular transport by the endothelial vesicular system as the route by which accumulated terbium had crossed the capillary wall in the rete mirabile of the eel. Expand
Openings Through Endothelial Cells Associated with Increased Microvascular Permeability
Reconstruction of openings in microvascular endothelium reveals that many pass through the periphery of the endothelial cells close to intact intercellular junctions, suggesting that the transcellular openings may develop from vacuolar channels. Expand