Electron Microscopic Radioautographic Detection of Sites of Protein Synthesis and Migration in Liver

Abstract

The sites of synthesis of proteins and their subsequent migration in rat liver have been studied during a 75 min period after labeling of liver-slice proteins by exposure to leucine-H(3) for 2 min. Incorporation of the label into protein began after 1 min and was maximal by 4 min. Electron microscopic radioautography showed that synthesis of proteins in… (More)

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