Electromembrane extraction of trace amounts of naltrexone and nalmefene from untreated biological fluids.

@article{Rezazadeh2011ElectromembraneEO,
  title={Electromembrane extraction of trace amounts of naltrexone and nalmefene from untreated biological fluids.},
  author={M. Rezazadeh and Y. Yamini and Shahram Seidi},
  journal={Journal of chromatography. B, Analytical technologies in the biomedical and life sciences},
  year={2011},
  volume={879 15-16},
  pages={
          1143-8
        }
}
Nalmefene and naltrexone are used to block the effects of narcotics and alcohol. In the present work, for the first time a microextraction technique was presented to reduce matrix interferences and improve detection limits of the drugs in urine and plasma samples. Electromembrane extraction (EME) followed by high performance liquid chromatography (HPLC) coupled with ultraviolet (UV) detection was optimized and validated for quantification of nalmefene and naltrexone from biological fluids. The… Expand
Electromembrane extraction of stimulating drugs from undiluted whole blood.
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